Huning Family Supports Parkinson’s Disease Research at UNM

Louis Hun­ing

Eva Chi, assis­tant pro­fes­sor of Chem­i­cal and Nuclear Engi­neer­ing, has devoted her career to study­ing the pro­teins that cause neu­rode­gen­er­a­tive dis­or­ders such as Alzheimer’s and Parkinson’s dis­ease. Now, thanks to the gen­eros­ity of a promi­nent local fam­ily, her lab is closer to dis­cov­er­ing a cure for these diseases.

Parkinson’s dis­ease is caused by the buildup of pro­tein within brain cells, caus­ing tremors, loss of bal­ance and dif­fi­culty mov­ing. For the Hun­ing fam­ily of Los Lunas, the fight against this dis­ease is per­sonal; it has affected the entire fam­ily. Fam­ily mem­bers have pledged $50,000 per year for the next three years to sup­port Chi’s research on these proteins.

Louis Hun­ing, a for­mer mayor of Los Lunas, is among the fam­ily mem­bers who have been affected by this dis­ease. He says the fight for a cure is a gift for future generations.

We’re just about to where there will be a cure for Parkinson’s,” Hun­ing said. “It would be a shame to not find that link in solv­ing this prob­lem because of money.”

Our fam­ily has suf­fered through two gen­er­a­tions of early onset Parkinson’s dis­ease,” said Mar­garet Bell, a local real­tor and Hun­ing fam­ily mem­ber. “Our goal with this research is the devel­op­ment of a diag­nos­tic test that will allow for pre­ven­tion so that the next gen­er­a­tion of our fam­ily and other fam­i­lies will not be affected by this ter­ri­ble disease.”

Part of Chi’s research is focused on iden­ti­fy­ing the pro­teins that cause Parkinson’s dis­ease and design­ing a method to detect their toxicity.

This knowl­edge will not only help us to bet­ter under­stand how pro­tein aggre­gates kill brain cells, but will also be used to screen for poten­tial drug com­pounds that can inhibit tox­i­c­ity,” Chi said.

Ini­ti­at­ing a new research project is often the tallest hur­dle for a new inves­ti­ga­tor. The Catch-22 in sci­en­tific research is that inves­ti­ga­tors must show good results in pre­lim­i­nary data to get fund­ing for their research. Yet, it takes seed fund­ing to con­duct the ini­tial research to pro­duce that pre­lim­i­nary data.

Thanks to the Hun­ings’ gen­eros­ity, Chi has cleared that first hur­dle. She has added a post­doc­toral researcher to her staff and has ramped up the ini­tial phase of research.

Once those pre­lim­i­nary results are in hand, Chi will be able to apply for fund­ing from fed­eral agen­cies such as the National Insti­tutes of Health and the National Sci­ence Foun­da­tion. Both agen­cies require sub­stan­tial pre­lim­i­nary data of pro­posed research.

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