STC.UNM recently celebrated the faculty, staff and students at the university who have been issued patents and disclosed copyrights over the last year.  The STC.UNM Creative Awards recognized the importance of the discoveries and celebrate the intellectual spirit of the award winners.

Below is a list of faculty, staff and students who have been granted patents over the last year.

Steven R.J. Brueck,Distinguished Professor Depts. of Electrical & Computer Engineering and Physics & Astronomy; director, Center for High Technology Materials

"Nanostructured Separation and Analysis Devices for Biological Membranes" - RE41, 762

This patent relates to a laboratory analogue in which a cell wall (a lipid membrane) is stretched over nanoscaled features etched into a substrate and different species confined within the membrane are separated by differential mobility through and along the membrane.

"Fabrication of Enclosed Nanochannels Using Silica Nanoparticles" - 7,825,037

This patent relates to a simple and facile technology for producing nanochannels by: first defining the channels in photo resist using interferometric lithography; second, filling the space around the photo resist with silica nanoparticles which are spun onto the wafer a monolayer at a time; and third removing the photo resist by heating the wafer in an oxygen ambient.

"Method and Apparatus for Producing Interferometric Lithography Patterns with Circular Symmetry" - 7,794,904

This patent outlines techniques to produce large arrays of circular fringes.

"Self-Aligned Spatial Frequency Doubling" - 7,906,275

This patent relates to methods for self-aligned spatial frequency doubling in one dimension and also in two dimensions.

"Nanostructured Separation and Analysis Devices for Biological Membranes" - RE42, 249

This patent relates to a nanostructured device comprising a substrate including nanotroughs therein; and a lipid bilayer suspended on or supported in the substrate.

Daniel F. Cimino, research specialist, Dept. of Cell Biology & Physiology; Cristian G. Bologa, research associate professor, Dept. of Biochemistry & Molecular Biology; Tudor I. Oprea, professor, Dept. of Biochemistry & Molecular Biology; Eric R. Possnitz, professor, Dept. of Cell Biology & Physiology; Larry A. Sklar, Regents' Professor of Pathology, Distinguished University Professor, Department of Pathology

"Compounds for Binding to ER alpha/beta and GPR30, Methods of Treating Disease States and Conditions Mediated through These Receptors and Identification Thereon" - 7,875,721

This patent relates to the field of molecular biology/pharmacology and provides compounds which modulate the effects of GPR30 as well as the classical estrogen receptors alpha and beta (ERα and ERβ).  These compounds may function as agonists and/or antagonists of one or more of the disclosed estrogen receptors.

Laurence Cole, professor, Depts. of Obstetrics & Gynecology and Biochemistry & Molecular Biology

"Hyperglycosylated HCG (Invasive Trophoblast Antigen) in the Differential Diagnosis of Malignant or Invasive Trophoblastic Disease" - 7,871,762

This patent relates to methods for detecting the presence or absence of invasive trophoblast cells.

"Method of Treating Cancer and Identifying Novel Anti-Cancer Compounds" - 7,708,991

This patent relates to compositions and methods for treating cancer, especially epithelial and eutopic cancers using inhibitors of H-HCG or .beta.-H-HCG, as well as vaccines for use in oncostasis or reducing the likelihood of recurrence of cancer after remission.

Abhaya Datye, Distinguished Professor, Dept. of Chemical & Nuclear Engineering; Hien Pham, research assistant professor, Dept. of Chemical & Nuclear Engineering; Timothy L. Ward, professor, Dept. of Chemical & Nuclear Engineering.

"Monodisperse Mesoporous Silica Microspheres Formed by Evaporation-Induced Self-Assembly of Surfactant Templates in Aerosols" - 7,879,304

This patent relates to evaporation induced self-assembly (EISA) within microdroplets produced by a vibrating orifice aerosol generator (VOAG) for the production of monodisperse mesoporous silica particles.

L. Ralph Dawson, research professor, Dept. of Electrical & Computer Engineering, Center for High Technology Materials; Ganesh Balakrishnan, assistant professor, Dept. of Electrical & Computer Engineering, Center for High Technology Materials

"Hybrid Integration Based on Wafer-Bonding of Devices to AISb Monolithically Grown on Si" - 7,700,395

This patent relates to embodiments that provide a semiconductor fabrication method including a combination of monolithic integration techniques with wafer bonding techniques.

Vojo P. Deretic, professor, Dept. Molecular Genetics & Microbiology; Graham Timmins, associate professor, College of Pharmacy

"Diagnosis of P. aeruginosa Infection in the Lungs of Patients" - 7,717,857

This patent relates to methods for detecting P. aeruginosa infection and bacterial burden in the lungs of patients who are at risk for P. aeruginosa infections, especially including patients with Cystic Fibrosis (CF).

"Non-Invasive Rapid Diagnostic Test for M. Tuberculosis Infection" - 7,897,400

This patent relates to a test for detecting a Mycobacterium tuberculosis (tuberculosis or TB) infection in a patient or subject, specifically a diagnostic test, including a breath test, whereby patients are provided a small dose of an isotopically labeled TB drug, Isoniazid (INH) orally or directly to the lungs of the patient or subject.

Andrew Frauenglass, research engineer 2, Center for High Technology Materials; Alexander K. Raub, Post-Doctoral Fellow, Center for High Technology Materials

"Self-Aligned Spatial Frequency Doubling" - 7,906,275

This patent relates to methods for self-aligned spatial frequency doubling in one dimension and also in two dimensions.

Sang Han, associate professor, Depts. of Chemical & Nuclear Engineering Electrical & Computer Engineering

"Threading-Dislocation-Free Nanoheteroepitaxy of GE on SI Using Self-Directed Touch-Down of GE through a Thin SIO2 Layer" - 7,888,244

This patent relates to a method of forming a virtually defect-free lattice mismatched nanoheteroepitaxial layer.

Linnea K. Ista, research scientist 2, Center for Biomedical Engineering, Ph.D. Graduate Student, Dept. of Biology;

These two patents are divisional patents coming from the same parent patent: hence the name is the same.

"Nanostructured Separation and Analysis Devices for Biological Membranes" - RE41,762, RE42,249

This patent relates to a laboratory analogue in which a cell wall (a lipid membrane) is stretched over nanoscaled features etched into a substrate and different species confined within the membrane are separated by differential mobility through and along the membrane.

This patent relates to a nanostructured device comprising a substrate including nanotroughs therein; and a lipid bilayer suspended on or supported in the substrate.

Ravinder (Ravi) Jain, professor, Dept. of Electrical and Computer Engineering, Center for High Technology Materials

"Precisely Wavelength-Tunable and Wavelength-Switchable Narrow Linewidth Lasers" - RE41 642

This patent relates to tunable fiber lasers and provides for a rapidly switchable multi-wavelength source that is relatively easy to manufacture for any customized set of arbitrary channels.

Walter Kisiel, Professor Emeritus, Department of Pathology

"Compositions and Methods Useful for the Diagnosis and Treatment of Heparin Induced Thrombocytopenia/Thrombosis" - 7,728,115

This patent relates compositions, kits and methods comprising a monoclonal antibody which shares key functional properties with the polyclonal antibodies which participate in the pathogenesis of heparin induced thrombocytopenia/thrombosis (HIT/HITT) in a mammal.

Walter Kisiel, Hitendra Chand, research assistant professor, Dept. of Pathology

"Human Kunitz-Type Inhibitor with Enhanced Antifibrinolytic Activity" - 7,910,550

This patent relates to a human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making and methods of use.

Eric R. Possnitz, professor, Dept. of Cell Biology & Physiology; Peter C. Simons, research assistant professor, Cancer Research and Treatment Center; Angela Wandinger-Ness, professor, Dept. of Pathology

"Glutathione Beads and GST Fusion Proteins" - 7,785,900

This patent relates generally to glutathione derivatized beads which are adapted for use in conjunction with glutathione-S-transferase fusion proteins (generally, GST fusion proteins, which contain a fluorescent label such as fluorescent green protein) for use in flow cytometry.

Tamara Roitbak, research assistant professor, Dept. of Neurosurgery; Elsa Romero, Health Sciences research tech 3; Dept. of Pathology; Angela Wandinger-Ness, professor, Dept. of Pathology

"Human Renal Stem Cells" - 7,776,592

This patent relates to human renal stem cells isolated from the papillary region of the human kidney and methods of isolating the same.

Wolfgang G. Rudolph, Regent's Professor, Dept. of Physics & Astronomy

"System and Method for Ratiometric Non-linear Coherent Imaging" - 7,869,051

This patent relates to a system and method of coherent imaging.  The system includes a light source adapted to provide coherent light to illuminate a sample resulting in optically mixed coherent signals and a detector adapted to receive the optically mixed coherent signals and produce an output signal in response thereto.

Edl Schamiloglu, professor, Dept. of Electrical & Computer Engineering; Mikhail I. Fuks, research professor, Dept. of Electrical & Computer Engineering

"Magnetron Having a Transparent Cathode and Related Methods of Generating High Power Microwaves" - 7,696,696

This patent relates to a magnetron having a cathode and related methods of generating high power microwaves.

Edl Schamiloglu, professor, Dept. of Electrical & Computer Engineering; Mikhail I. Fuks, research professor, Dept. of Electrical & Computer Engineering; Sarita Prasad, research assistant, Dept. of Electrical & Computer Engineering


"Eggbeater Transparent Cathode for Magnetrons and Ubitrons and Related Methods of Generating High Power Microwaves" - 7,893,621

This patent relates to an eggbeater transparent cathode for magnetrons and ubitrons and related methods for generating high power microwaves.

Larry A. Sklar, Regents' Professor of Pathology, Distinguished University Professor, Dept. of Pathology; Bruce Edwards, research professor, Dept. of Pathology

"Flow Cytometry for High Throughput Screening" - 7,842,244

This patent relates to a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means for introducing a separation gas between each of the plurality of samples in the fluid flow stream; and means for selectively analyzing each of the plurality of samples for the particles.  The present invention also provides a flow cytometry method employing such an apparatus.

Larry A. Sklar, Regents' Professor of Pathology, Distinguished University Professor, Dept. of Pathology; Peter C. Simons, research assistant Professor Cancer Research and Treatment Center; Eric R. Possnitz, Professor Dept. of Cell Biology & Physiology; Angela Wandinger-Ness, professor, Dept. of Pathology

"Glutathione Beads and GST Fusion Proteins" - 7,785,900

This patent relates generally to glutathione derivatized beads which are adapted for use in conjunction with glutathione-s-transferase fusion proteins (generally, GST fusion proteins, which contain a fluorescent label such as fluorescent green protein) for use in flow cytometry.

James L. Thomas, associate professor, Dept. of Physics & Astronomy; Sarita Prasad, research assistant, Dept. of Electrical & Computer Engineering

"System and Method for Ratiometric Non-linear Coherent Imaging" - 7,869,051

This patent relates to a system and method for coherent imaging.  The system includes a light source adapted to provide coherent light to illuminate a sample resulting in optically mixed coherent signals and a detector adapted to receive the optically mixed coherent signals and produce an output signal in response thereto.

Graham Timmins, associate professor, College of Pharmacy

"System and Methods for Measuring a Skin Protection Factor" - 7,888,001

This patent relates to a system and methods of establishing a Melanocyte Protection Factor (MPF), which indicates the level of protection against DNA damage to a target cell, such as the level of protection a particular sunscreen offers against UVA rays when compared to the unprotected case, i.e., no sunscreen.

Xingmao Jiang, research assistant professor, Dept. of Chemical and Nuclear Engineering; C. Jeffrey Brinker, Distinguished Professor, Dept. of Chemical & Nuclear Engineering

"Hollow Sphere Metal Oxides" - 7,744,673

This patent relates to methods for fabricating hollow spheres and nanofoams.

COPYRIGHTS

William G. Woodall,
professor, Dept. of Communications & Journalism, sr. research scientist, Center on Alcoholism, Substance Abuse and Addictions

"Uconsiderthis: A Website to Prevent Risky College Student Alcohol Consumption"

A computer program designed to help college students understand the risks associated with alcohol consumption and how to manage those risks safely by teaching them about the consequences of binge drinking and by exploring different concepts that can have an effect on students' decisions about how much, when and where to drink.

WayToServe.org is a comprehensive multimedia website designed to effectively train on- premise (liquor by the drink) servers in the responsible service of alcohol.

Courtney Johnson, professor, Dept. of Pediatrics

"The Art and Science of Mentoring"

A didactic concept and tool for mentorship in diverse fields for individuals, small or large groups in medicine, law, business, arts and sciences, even auto mechanics.

Svetlana Poroseva, assistant professor, Dept. of Mechanical Engineering

"Power System Graph Converter"

The Power System Graph Converter is software that allows a designer to draw the diagram of a system with sources and sinks such as a power system and then to convert automatically the diagram into a structured adjacency matrix or list suitable for computational analysis.

For a related story visit: Sklar Named STC.UNM Innovation Fellow for 2011.